- William A. Rosenthall Judaica Collection - Postcards3,831
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19952,662
- SCDOT Photographs: Properties in the Right-of-Way2,276
- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.1,613
- William A. Rosenthall Judaica Collection - Prints and Photographs1,588
- YWCA of Greater Charleston, Inc., Records, 1906 - 20071,405
- Septima P. Clark Papers, ca. 1910-ca. 19901,227
- John Henry Dick Collection1,185
- Gertrude Sanford Legendre Papers, 1844-19961,176
- Civic Services Committee Papers1,145
- Bernice Robinson Papers, 1920-19891,131
- College of Charleston Buildings and Grounds Photograph Collection1,059
- Photos from the Records of The Historic Preservation Planner, BCD-COG985
- City of Charleston Board of Architectural Review Photographs Collection913
- Cleveland L. Sellers, Jr. Papers, 1934 - 2003902
- This is Charleston894
- William ("Bill") Saunders Papers, circa 1950 - 2004891
- Charleston Naval Shipyard Photographs819
- Ball Family Papers, 1631-1895798
- McLeod Family Papers, 1873-1990 (bulk 1900-1965)787