- Charles Fraser's Sketchbook, 1796-1805115
- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.1,494
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19952,136
- Charleston City Directories1
- Charleston City Records Collection1
- Charleston Fire Department Record Book1
- Charleston Iron Works records, 19072
- Charleston Museum Illustrated Newspapers Collection85
- Charleston Naval Shipyard Newsletters20
- Charleston Slave Passes3
- City Engineers's Plat Book, 1671-1951256
- City Year Books for Charleston, South Carolina, 1880-195136
- City of Charleston Board of Architectural Review Photographs Collection105
- City of Charleston Collection2
- City of Charleston Zoning Ordinances1
- City of Charleston, SC, Report of the City Planning and Zoning Commission, Zone Maps10
- Civic Services Committee Papers1
- Cleveland L. Sellers, Jr. Papers, 1934 - 20035
- Cohen, Emanuel, Moses, Seixas Family Papers1
- College of Charleston Magazines48