- Miriam DeCosta Seabrook and Herbert U. Seabrook Papers, 1882-199560
- J. Arthur Brown Papers, 1937 - 198858
- Harby, Moise, Levy, Moses, Davis Family Photographs55
- Cleveland L. Sellers, Jr. Papers, 1934 - 200347
- L.A. Hall Civil War and Reconstruction Eras Stereoscopic Images45
- Moses Family Papers45
- Lazarus and Hirsch Family Papers43
- Rabbi Jacob S. Raisin Papers41
- 1938 Tornado Photograph Collection37
- Illustrated Newspaper Clippings, 1840-191737
- Mazyckborough-Wraggborough Photograph Survey37
- Eola Willis Cuban photograph collection, circa 1895-191036
- Rice Harvest at Mulberry Plantation (Berkeley County, SC)34
- Edmondston-Alston Photograph Collection33
- Anita Pollitzer Family Papers28
- Millicent E. Brown Papers, 1949 - 200326
- Drayton Papers, 1701-200424
- Maynard Pearlstine Travel Albums and Sketches, 1936-200624
- Esau Jenkins Papers, 1963-200323
- Dientje Krant Kalisky Adkins Photographs, 1938-199622