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Collection
- Lynch Family Letters, 1858-186653
- Edmondston-Alston Family Letters and Paper Materials, 1782-191913
- Heyward and Ferguson Family Papers, 1806-192313
- Barnwell Family Papers10
- John R. Beaty Letters10
- Allston Family Papers, 1730-19015
- Slave Records in the Discrete Manuscript Collection4
- Grimke family papers, 1678-19773
- Walter Pantovic Slavery and African American History Collection3
- Confederate Military Correspondence2
- Drayton Family Papers, 1837-18692
- Letters to Alfred Wardlaw, 1857-18622
- Ball Family Papers, 1631-18951
- South Carolina Historical Society Manuscripts1
- Thomas J. Tobias papers, ca. 1790-19701
- Wilkinson-Keith Family Papers1