- Charleston Fire Department Record Book1
- Charleston Naval Shipyard Newsletters20
- Charleston Slave Passes3
- City Engineers's Plat Book, 1671-1951256
- City Year Books for Charleston, South Carolina, 1880-195136
- City of Charleston Board of Architectural Review Photographs Collection105
- City of Charleston Collection2
- City of Charleston Zoning Ordinances1
- City of Charleston, SC, Report of the City Planning and Zoning Commission, Zone Maps10
- Civic Services Committee Papers1
- Cleveland L. Sellers, Jr. Papers, 1934 - 20031
- Cohen, Emanuel, Moses, Seixas Family Papers1
- College of Charleston Magazines48
- College of Charleston Pamphlet Collection4
- College of Charleston Stereoscope Views2
- Craft and Crum Families, 1780-20075
- Dientje Krant Kalisky Adkins Photographs, 1938-19961
- Edmondston-Alston Family Letters and Paper Materials, 1782-19191
- Edmondston-Alston Photograph Collection4
- Eighteenth & Nineteenth Century Correspondence Collection2