Edward Barnwell writes to father, William H. W. Barnwell, about his employment in Charleston. After a brief stint with Coffin & Pringle Co., Barnwell has taken a more advantageous position with commissions merchant, Mr. Hubert. Barnwell also mentions a smallpox outbreak that has hit Charleston and the countryside and notes a bad reaction his brother, Robert Woodward Barnwell, has had to the smallpox vaccination. Barnwell suggests having his father's "little negroes" inoculated as well if enough vaccine can be found. January 19, 1854.