- Accounts and Estate Administration Books, 1824-18525
- Coffin Point Plantation Journals, 1800-18165
- L. Mendel Rivers Papers, 1940-19625
- Bowman Family Papers, 1835-18924
- Chesnut Family Papers, 1741-19004
- Cote Bas and Mepkin Plantations Journals, 1865-18774
- Hasell Family Papers, 1803 - 18844
- Loose Papers of the Summerville Museum and Research Center4
- Horlbeck Brothers Records, 1824-18603
- Mulberry Plantation Journals, 1853-1908 (bulk 1853-1889)3
- Pringle-Garden Family Papers, 1701-18823
- Rose Hill Plantation Time Books, 18783
- Senator Burnet R. Maybank Papers, 1914-19733
- Account Books of Benjamin Perry’s Wards, 1841-18642
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19952
- Deas Family Papers and Research, 1766-19762
- Elizabeth W. Allston Pringle Family Papers, 1861-19262
- Emily Clarkson Ball Grainger Family Papers, 1839-1962 (bulk 1926-1950)2
- Eugene C. Hunt Papers, 1834 - 19942
- James W. Miles Papers, ca. 1840-18752